Pathogenic Aβ production by heterozygous PSEN1 mutations is intrinsic to the mutant protein and not mediated by conformational hindrance of wild-type PSEN1

Autor: Kurth, Vanessa, Ogorek, Isabella, Münch, Carolina, Lopez-Rios, Javier, Ousson, Solenne, Lehmann, Sandra, Nieweg, Katja, Roebroek, Anton J.M., Pietrzik, Claus U., Beher, Dirk, Weggen, Sascha
Zdroj: In Journal of Biological Chemistry August 2023 299(8)
Databáze: ScienceDirect