Stable IgG-like Bispecific Antibodies Directed toward the Type I Insulin-like Growth Factor Receptor Demonstrate Enhanced Ligand Blockade and Anti-tumor Activity

Autor: Dong, Jianying, Sereno, Arlene, Snyder, William B., Miller, Brian R., Tamraz, Susan, Doern, Adam, Favis, Michael, Wu, Xiufeng, Tran, Hon, Langley, Emma, Joseph, Ingrid, Boccia, Antonio, Kelly, Rebecca, Wortham, Kathleen, Wang, Qin, Berquist, Lisa, Huang, Flora, Gao, Sharon X., Zhang, Ying, Lugovskoy, Alexey, Martin, Shelly, Gouvis, Heather, Berkowitz, Steven, Chiang, Gisela, Reff, Mitchell, Glaser, Scott M., Hariharan, Kandasamy, Demarest, Stephen J.
Zdroj: In Journal of Biological Chemistry 11 February 2011 286(6):4703-4717
Databáze: ScienceDirect