Why Is Quinidine an Inhibitor of Cytochrome P450 2D6?: THE ROLE OF KEY ACTIVE-SITE RESIDUES IN QUINIDINE BINDING

Autor: McLaughlin, Lesley A. ‡, 1, Paine, Mark J.I. ‡, 1, Kemp, Carol A. §, Maréchal, Jean-Didier §, ¶, Flanagan, Jack U. , Ward, Clive J. , Sutcliffe, Michael J. §, ¶, Roberts, Gordon C.K. §, 2, Wolf, C. Roland ‡, 3
Zdroj: In Journal of Biological Chemistry 18 November 2005 280(46):38617-38624
Databáze: ScienceDirect