Farnesyltransferase inhibitors interact synergistically with the Chk1 inhibitor UCN-01 to induce apoptosis in human leukemia cells through interruption of both Akt and MEK/ERK pathways and activation of SEK1/JNK

Autor: Dai, Yun, Rahmani, Mohamed, Pei, Xin-Yan, Khanna, Payal, Han, Song Iy, Mitchell, Clint, Dent, Paul, Grant, Steven *
Zdroj: In Blood 15 February 2005 105(4):1706-1716
Databáze: ScienceDirect