Pediatric Dose Determinations for the Phase I Study of the DOT1L Inhibitor, EPZ-5676, in MLL-r Acute Leukemia: Leveraging Early Clinical Data in Adults through Physiologically-Based Pharmacokinetic Modeling

Autor: Waters, Nigel J *, Thomson, Blythe, Gardner, Iain *, Johnson, Trevor N *, Olhava, Edward J *, Pollock, Roy M *, Legler, Michelle *, Copeland, Robert A, Hedrick, Eric E *
Zdroj: In Blood 6 December 2014 124(21):3619-3619
Databáze: ScienceDirect