Global alteration of the drug-binding pocket of human P-glycoprotein (ABCB1) by substitution of fifteen conserved residues reveals a negative correlation between substrate size and transport efficiency
Autor: | Vahedi, Shahrooz, Chufan, Eduardo E., Ambudkar, Suresh V. |
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Zdroj: | In Biochemical Pharmacology 1 November 2017 143:53-64 |
Databáze: | ScienceDirect |
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