Biotechnological synthesis of drug metabolites using human cytochrome P450 2D6 heterologously expressed in fission yeast exemplified for the designer drug metabolite 4′-hydroxymethyl-α-pyrrolidinobutyrophenone
Autor: | Peters, Frank T., Dragan, Calin-A., Wilde, Désirée R., Meyer, Markus R., Zapp, Josef, Bureik, Matthias, Maurer, Hans H. |
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Zdroj: | In Biochemical Pharmacology 1 August 2007 74(3):511-520 |
Databáze: | ScienceDirect |
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