Biotechnological synthesis of drug metabolites using human cytochrome P450 2D6 heterologously expressed in fission yeast exemplified for the designer drug metabolite 4′-hydroxymethyl-α-pyrrolidinobutyrophenone

Autor: Peters, Frank T., Dragan, Calin-A., Wilde, Désirée R., Meyer, Markus R., Zapp, Josef, Bureik, Matthias, Maurer, Hans H.
Zdroj: In Biochemical Pharmacology 1 August 2007 74(3):511-520
Databáze: ScienceDirect