| Popis: |
Most proteins contain tyrosine residues with a natural abundance of about 3% [1]. Tyrosine (one letter abbreviation, Y; three letter abbreviation, Tyr; also known as 4-hydroxyphenylalanine) is a non-essential amino acid and a member of the aromatic amino acid group. Tyrosine is mildly hydrophilic, a characteristic feature that is explained by the rather hydrophobic aromatic benzene ring carrying a hydroxyl group. As a consequence, tyrosine is often surface-exposed in proteins (only 15% of tyrosine residues are buried inside a protein) and therefore should be available for modification such as nitration by various |
