Evolution of focal choroidal excavation in ABCA4-related retinopathy

Autor: Matthew D. Benson, Carly B. Feldman, Wadih M. Zein
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: American Journal of Ophthalmology Case Reports, Vol 28, Iss , Pp 101740- (2022)
Druh dokumentu: article
ISSN: 2451-9936
DOI: 10.1016/j.ajoc.2022.101740
Popis: Purpose: To report long-term evolution of unilateral focal choroidal excavation in a patient with ABCA4-related retinopathy. Observations: A 51-year-old female with ABCA4-related retinopathy developed a small juxtafoveal defect in Bruch's membrane in a region of macular atrophy in her left eye. In follow-up, the defect widened and subsequently developed into a focal choroidal excavation. Over the next 8 years, serial optical coherence tomography imaging illustrated the conversion of the focal choroidal excavation from conforming subtype into non-conforming subtype with eventual macular hole formation. Conclusions and importance: The long-term follow-up of a patient with serial imaging highlights the potential dynamic nature of focal choroidal excavation in ABCA4-related retinopathy. Progressive retinal degeneration may influence focal choroidal excavation morphology and may promote macular hole formation.
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