Fecal amine metabolite analysis before onset of severe necrotizing enterocolitis in preterm infants: a prospective case–control study

Autor: N. Deianova, S. el Manouni el Hassani, E. A. Struijs, E. E. W. Jansen, A. Bakkali, M. A. van de Wiel, W. P. de Boode, C. V. Hulzebos, A. H. van Kaam, B. W. Kramer, E. d’Haens, D. C. Vijlbrief, M. M. van Weissenbruch, W. J. de Jonge, M. A. Benninga, H. J. Niemarkt, N. K. H. de Boer, T. G. J. de Meij
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-022-16351-8
Popis: Abstract Infants developing necrotizing enterocolitis (NEC) have a different metabolomic profile compared to controls. The potential of specific metabolomics, i.e. amino acids and amino alcohols (AAA), as early diagnostic biomarkers for NEC is largely unexplored. In this multicenter prospective case–control study, longitudinally collected fecal samples from preterm infants (born
Databáze: Directory of Open Access Journals
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