| Autor: |
WANG Mengmeng, LIU Xiaobin, LI Li, WANG Liyuan, WANG Yuxia |
| Jazyk: |
čínština |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Kouqiang yixue, Vol 44, Iss 9, Pp 670-677 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1003-9872 |
| DOI: |
10.13591/j.cnki.kqyx.2024.09.006 |
| Popis: |
Objective To investigate, before and after sucrose challenge, the difference of saliva microbiome between caries-free (CF) and caries-active (CA) individuals, and to explore the potential key microorganisms that is more susceptible to sucrose challenge. Methods Eighteen systemic healthy volunteers, among which 8 were caries-free and 10 were caries-active, were recruited. Saliva samples were collected pre-treatment and at 30 min and 2 h after the sucrose treatment. Microbial diversity and community structure were analyzed and compared using Illumina sequencing platform. Results The diversity and abundance of saliva samples from caries-free individuals was similar to that from caries-active individuals before sucrose treatment. After 2 h of treatment, the microbial diversity of the CA group was significantly higher than that of the CF group (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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