Modified reverse shock index predicts early outcomes of heart failure with reduced ejection fraction

Autor: Gyu Chul Oh, Seokyung An, Hae‐Young Lee, Hyun‐Jai Cho, Eun‐Seok Jeon, Sang Eun Lee, Jae‐Joong Kim, Seok‐Min Kang, Kyung‐Kuk Hwang, Myeong‐Chan Cho, Shung Chull Chae, Dong‐Ju Choi, Byung‐Su Yoo, Kye Hun Kim, Sue K. Park, Sang Hong Baek
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: ESC Heart Failure, Vol 9, Iss 5, Pp 3232-3240 (2022)
Druh dokumentu: article
ISSN: 2055-5822
DOI: 10.1002/ehf2.14031
Popis: Abstract Aims Increased blood pressure (BP) and decreased heart rate (HR) are signs of stabilization in patients admitted for acute HF. Changes in BP and HR during admission and their correlation with outcomes were assessed in hospitalized patients with heart failure (HF) with reduced ejection fraction (HFrEF). Methods A novel modified reverse shock index (mRSI), defined as the ratio between changes in systolic BP and HR during admission, was devised, and its prognostic value in the early outcomes of acute HF was assessed using the Korean Acute HF registry. Results Among 2697 patients with HFrEF (mean age 65.8 ± 14.9 years, 60.6% males), patients with mRSI ≥1.25 at discharge were significantly younger and were more likely to have de novo HF. An mRSI ≥1.25 was associated with a significantly lower incidence of 60‐day and 180‐day all‐cause mortality [hazard ratio (HR) 0.49, 95% confidence interval (CI) 0.31–0.77; HR 0.62, 95% CI 0.45–0.85, respectively], compared with 1 ≤ mRSI
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