Central and humoral mechanisms for arterial hypertension in women

Autor: V I Podzolkov, A E Bragina, J N Rodionova, J A Koloda
Jazyk: ruština
Rok vydání: 2015
Předmět:
Zdroj: Системные гипертензии, Vol 12, Iss 1, Pp 76-82 (2015)
Druh dokumentu: article
ISSN: 2075-082X
2542-2189
Popis: The article discusses various mechanisms of arterial hypertension (AH) development in postmenopausal women. It includes literature data on the sexual hormones, namely estrogen and progesterone deficit and androgen overproduction, influence on the blood pressure level and metabolic disorder. Special focus is on the role of renin-angiotensin-aldosterone system in AH pathogenesis. Separate paragraph is focused on the role autonomous nervous system dysfunction and disorders of biogenic amines metabolism in the vascular and autonomic disorders in climacteric syndrome, as well as the contribution of the humoral shifts typical for central obesity, such as hyperinsulinemia, and hyperleptinemia.
Databáze: Directory of Open Access Journals