| Autor: |
Kyung‐Nam Koh, Jung‐Man Namgoong, Hee Mang Yoon, Young Ah Cho, Se Hoon Choi, Juhee Shin, Sung Han Kang, Jin Kyung Suh, Hyery Kim, Seak Hee Oh, Kyung Mo Kim, Dae Yeon Kim, Ho Joon Im |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Cancer Medicine, Vol 10, Iss 10, Pp 3261-3273 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2045-7634 |
| DOI: |
10.1002/cam4.3897 |
| Popis: |
Abstract Background Prognostic factors in hepatoblastoma need to be reevaluated considering the advances in treatment modalities. The study aimed to evaluate current outcomes of hepatoblastoma and reappraise the association of prognostic factors, including pre‐treatment extent of tumor (PRETEXT) stage with annotation factors and Children's Hepatic tumors International Collaboration‐Hepatoblastoma Stratification (CHIC‐HS) system, with survival outcomes. Methods We evaluated 103 consecutive patients with hepatoblastoma retrospectively according to the treatment period based on the introduction of a liver transplantation program. Results The 5‐year overall survival (OS), event‐free survival (EFS), and transplant‐free survival rates were 80.2%, 74.2%, and 61.8%, respectively. EFS and OS were improved significantly from 58.6% to 81.6% (P = 0.024) and from 58.6% to 90.8% (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
