A Unique Naphthone Derivative and a Rare 4,5-seco-Lanostane Triterpenoid from Poria cocos

Autor:	Ting Chen, La Hua, Guixin Chou, Xudong Mao, Xianliang Zou
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	Poria cocos lanostane triterpenoids naphthalenone derivative cancer cell line cytotoxic activity Organic chemistry QD241-441
Zdroj:	Molecules, Vol 23, Iss 10, p 2508 (2018)
Druh dokumentu:	article
ISSN:	1420-3049
DOI:	10.3390/molecules23102508
Popis:	A previously undescribed naphthalenone derivative, sohiracillinone (1), and a novel 4,5-seco-lanostane triterpenoid, 11β-ethoxydaedaleanic acid A (2) were isolated with two new lanostane triterpenoids, ceanphytamic acids A (3) and B (4), from the EtOH extract of Poria cocos along with 17 known compounds 5–21. The absolute configuration of sohiracillinone (1) was unambiguously identified by NMR and electronic circular dichroism (ECD) data. The structures of other new compounds were elucidated on the basis of NMR and mass spectroscopy (MS), and the cytotoxic activities of all the isolated components were evaluated.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/ff9f8d9014ee41c0a7a0bc4c51c4d0af Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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