Adverse Event Profiles of Adalimumab in Children: A Disproportionality Analysis

Autor:	Wenting Zhang, Ziqi Xu, Yamin Shu, Sainan Shu, Qilin Zhang
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	adalimumab adverse event children disproportionality analysis FAERS database Medicine Pharmacy and materia medica RS1-441
Zdroj:	Pharmaceuticals, Vol 17, Iss 8, p 1028 (2024)
Druh dokumentu:	article
ISSN:	1424-8247
DOI:	10.3390/ph17081028
Popis:	Background: Adalimumab has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of adult rheumatoid arthritis (RA), and subsequently approved for pediatric treatment of various autoimmune diseases in children of different ages. Due to genetic differences between children and adults in terms of physiology and immunity, there is a need to explore the safety of adalimumab in children in the real world. The aim of this study is to identify potential adverse event (AE) signals associated with the use of adalimumab in pediatric patients (
Databáze:	Directory of Open Access Journals
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