Epidural Xylazine Reduced Ketamine Anesthetic Requirements in Laparoscopic Ovariohysterectomy in the Dog

Autor: Hosein Ashegh, Mir Sepehr Pedram, Mahboobeh Abdi, Mohammad Abarkar, Mohamad Hejazi, Mohammad Mohsen Maghari, Jalal Rezaee, Hasan Tavakoi
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Iranian Journal of Veterinary Surgery, Vol 05, Iss 1-2, Pp 101-108 (2010)
Druh dokumentu: article
ISSN: 2008-3033
Popis: Objectives: To evaluate if epidural administration of xylazine could decrease the effective dose of intravenous ketamine for maintenance of general anesthesia in laparoscopic procedures and assessment of related complications during anesthesia. Design: Experimental Study. Animals: 20 Female dogs with 21.0 ± 3.0 kg weight and 18.0 ± 1.2 months age. Material and methods: Animals randomly divided into two groups (n=10). All dogs premedicated with acepromazine. Anesthesia induced by combination of ketamine and diazepam. In one group xylazine injected epidurally then all of them spayed by same laparoscopic method and repeated doses of ketamine for maintenance of anesthesia. Cardiopulmonary parameters such as SpO2 and ETCO2 during operation were recorded. Results: There were no significant differences in weight and age between two groups. Mean of ketamine administration in group 1 was 640 mg and in group 2 (have epidural administration of xylazine) was 270 mg. Conclusions and Clinical Relevance: Data analysis showed that epidural administration of xylazine, decreases the amount of ketamine needed to maintain anesthesia (P
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