| Autor: |
Tim J. Hartung, Christian Neumann, Thomas Bahmer, Irina Chaplinskaya-Sobol, Matthias Endres, Johanna Geritz, Karl Georg Haeusler, Peter U. Heuschmann, Hanna Hildesheim, Andreas Hinz, Sina Hopff, Anna Horn, Michael Krawczak, Lilian Krist, Jennifer Kudelka, Wolfgang Lieb, Corina Maetzler, Anja Mehnert-Theuerkauf, Felipe A. Montellano, Caroline Morbach, Sein Schmidt, Stefan Schreiber, Flo Steigerwald, Stefan Störk, Walter Maetzler, Carsten Finke |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
EClinicalMedicine, Vol 53, Iss , Pp 101651- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2589-5370 |
| DOI: |
10.1016/j.eclinm.2022.101651 |
| Popis: |
Summary: Background: Reliable estimates of frequency, severity and associated factors of both fatigue and cognitive impairment after COVID-19 are needed. Also, it is not clear whether the two are distinct sequelae of COVID-19 or part of the same syndrome.'' Methods: In this prospective multicentre study, frequency of post-COVID fatigue and cognitive impairment were assessed in n = 969 patients (535 [55%] female) ≥6 months after SARS-CoV-2 infection with the FACIT-Fatigue scale (cut-off ≤30) and Montreal Cognitive Assessment (≤25 mild, ≤17 moderate impairment) between November 15, 2020 and September 29, 2021 at University Medical Center Schleswig-Holstein, Campus Kiel and University Hospital Würzburg in Germany. 969 matched non-COVID controls were drawn from a pre-pandemic, randomised, Germany-wide population survey which also included the FACIT-Fatigue scale. Associated sociodemographic, comorbid, clinical, psychosocial factors and laboratory markers were identified with univariate and multivariable linear regression models. Findings: On average 9 months after infection, 19% of patients had clinically relevant fatigue, compared to 8% of matched non-COVID controls (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
