Lycorine impedes 7,12-dimethylbenz(a)anthracene exposed hamster oral carcinogenesis through P13K/Akt and NF-κB inhibition

Autor: Gan Yi, He Ai’e, Zhu Lilei, Yao Yao, Lv Chunhua
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Türk Biyokimya Dergisi, Vol 47, Iss 6, Pp 802-810 (2022)
Druh dokumentu: article
ISSN: 1303-829X
DOI: 10.1515/tjb-2021-0284
Popis: Oncogenic signaling pathways that are activated abnormally play a key activity in tumor initiation and development. This research aimed to examine the preventive efficiency of lycorine in the buccal pouch hamster tumor model based on its capacity to target phosphoinositide 3-kinase (PI3K)/Akt and nuclear factor-kappa B (NF-κB) signaling cascades.
Databáze: Directory of Open Access Journals