Assessment of Drug-Related Problems among Inpatients in a Tertiary Care Hospital of Eastern Nepal
| Autor: | Rashmi Adhikari, Prasanna Dahal, Sitaram Khadka, Shyam Kumar Mallik, Kadir Alam |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Journal of Karnali Academy of Health Sciences, Vol 4, Iss 1 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2616-0064 2676-1327 |
| Popis: | Background: Drug-related Problems are major safety concerns in hospitalized patients; failure to prevent those medications related errors may lead to therapeutic failure, adverse effects, and poor therapeutic outcomes. This study aims to assess drug-related problems in the medicine ward of a tertiary care hospital in Eastern Nepal. Methodology: Prospective observational study was conducted from March to August 2019. Descriptive analysis was performed, and Bivariate analysis using chi-square was used to test the association between demographic characteristics and drug-related problems. Results: 365 patients were selected, of which 96 patients had drug-related problems. A total of 127 drug-related problems were documented. The most common drug-related problems were drug and therapeutic duplication 31(24.4%), a drug prescribed but no clear indication 22(17.3%), potential ineffective therapy 16(12.6%), inappropriate duration 11(8.7%), and adverse drug reaction 10(7.8%). The majority of recommendations provided by the pharmacist were drug discontinuation 57(44.9%), followed by drug change 16(12.6%), and the need for antibiotic susceptibility testing 14(11%). Antimicrobials 75(59.1%) was the most frequent drug class involved in drug-related problems followed by Corticosteroids 12(9.4%), and Non-steroidal anti-inflammatory drugs 8(6.3%). A significant association with drug-related problems occurrences was found between age groups, length of hospital stay, and polypharmacy which was significant at p |
| Databáze: | Directory of Open Access Journals |
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