Adoption of the American Academy of Pediatrics’ neonatal hyperbilirubinemia guidelines and its effect on blood exchange transfusion rate in a tertiary care center in Amman, Jordan

Autor: Al-Lawama M, Al-Rimawi E, Al-Shibi R, Badran E
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Journal of Blood Medicine, Vol Volume 9, Pp 61-66 (2018)
Druh dokumentu: article
ISSN: 1179-2736
Popis: Manar Al-Lawama, Eman Al-Rimawi, Rawan Al-Shibi, Eman Badran Department of Pediatrics, The University of Jordan, School of Medicine, Amman, Jordan Introduction: Severe neonatal hyperbilirubinemia can cause mortality and serious morbidities. When phototherapy fails, neonates with severe hyperbilirubinemia should undergo double volume blood exchange transfusion (BET). As this procedure carries a significant risk of mortality and morbidity, adopting guidelines for the treatment of neonatal hyperbilirubinemia is critical to avoid hyperbilirubinemia toxicity and also the complication of an unindicated procedure. Methods: This study investigated the causes, complications, and trend of BET rate in our unit over a 13-year period. The medical charts and laboratory databases of all infants who underwent BET in Jordan University Hospital between 2003 and 2015 were retrospectively reviewed. Results: The rate of exchange cases decreased significantly after adopting the guidelines of American Academy of Pediatrics (P12 months of age. Conclusions: This study showed a clear decline in the rate of BET after implementing the guidelines of American Academy of Pediatrics. In addition to improving the strategies for the identification and follow-up of at-risk newborns, we should intensify our efforts to prevent the progression of neonatal hyperbilirubinemia to the exchange level by enhancing parents’ ­awareness of this potentially harmful neonatal condition. Keywords: neonate, exchange transfusion, hyperbilirubinemia, guidelines, Jordan
Databáze: Directory of Open Access Journals
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