Prevalence of chronic kidney disease and risk factors in North-Central Nigeria: a population-based survey

Autor: Timothy Olusegun Olanrewaju, Ademola Aderibigbe, Ademola Alabi Popoola, Kolawole Thomas Braimoh, Mikhail Olayinka Buhari, Olanrewaju Timothy Adedoyin, Sulyman Alege Kuranga, Sikiru Abayomi Biliaminu, Adindu Chijioke, Abdulwahab Akanbi Ajape, Diederick E Grobbee, Peter J Blankestijn, Kerstin Klipstein-Grobusch, the Ilorin Renal Study Group
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: BMC Nephrology, Vol 21, Iss 1, Pp 1-10 (2020)
Druh dokumentu: article
ISSN: 1471-2369
DOI: 10.1186/s12882-020-02126-8
Popis: Abstract Background Chronic kidney disease (CKD) is a growing challenge in low- and middle-income countries, particularly in sub-Saharan Africa. There is insufficient population-based data on CKD in Nigeria that is required to estimate its true burden, and to design prevention and management strategies. The study aims to determine the prevalence of CKD and its risk factors in Nigeria. Methods We studied 8 urban communities in Kwara State, North-Central zone of Nigeria. Blood pressure, fasting blood sugar, urinalysis, weight, height, waist circumference and hip circumference were obtained. Albuminuria and kidney length were measured by ultrasound while estimated glomerular filtration rate (eGFR) was derived from serum creatinine, using chronic disease epidemiology collaboration (CKD-EPI) equation. Associations of risk factors with CKD were determined by multivariate logistic regression and expressed as adjusted odds ratio (aOR) with corresponding 95% confidence intervals. Results One thousand three hundred and fifty-three adults ≥18 years (44% males) with mean age of 44.3 ± 14.4 years, were screened. Mean kidney lengths were: right, 93.5 ± 7.0 cm and left, 93.4 ± 7.5 cm. The age-adjusted prevalence of hypertension was 24%; diabetes 4%; obesity 8.7%; albuminuria of > 30 mg/L 7%; and dipstick proteinuria 13%. The age-adjusted prevalence of CKD by estimated GFR
Databáze: Directory of Open Access Journals