Functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease

Autor: Satoshi Watanabe, Tohru Kurotani, Tomofumi Oga, Jun Noguchi, Risa Isoda, Akiko Nakagami, Kazuhisa Sakai, Keiko Nakagaki, Kayo Sumida, Kohei Hoshino, Koichi Saito, Izuru Miyawaki, Masayuki Sekiguchi, Keiji Wada, Takafumi Minamimoto, Noritaka Ichinohe
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-25487-6
Popis: Non-human primate models of autism spectrum disorder (ASD) are few and not well characterised. Here, the authors describe synaptic function and gene expression changes in a marmoset model of ASD from birth to juvenile, highlighting its similarity to features observed in human ASD.
Databáze: Directory of Open Access Journals
Externí odkaz: