Antifungal Activity-Guided Analysis of Actinostemma lobatum Extracts through Serial Sub-fractions

Autor: Seonwoo Choi, Song Hee Lee, Byeong Su Hwang, Young Taek Oh, Junhyun Jeon
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: The Plant Pathology Journal, Vol 40, Iss 2, Pp 218-224 (2024)
Druh dokumentu: article
ISSN: 1598-2254
2093-9280
DOI: 10.5423/PPJ.NT.11.2023.0152
Popis: Plants are treasure trove of novel compounds that have potential for antifungal chemicals and drugs. In our previous study, we had screened plant extracts obtained from more than eight hundred plant materials collected in Korea, and found that butanol fraction of the Actinostemma lobatum were most potent in suppressing growth of diverse fungal pathogens of plants. Here in this study, we describe further analysis of the butanol fraction, and summarize the results of subsequent antifungal activity test for the sub-fractions against a selected set of plant pathogenic fungi. This line of analyses allowed us to identify the sub-fractions that could account for a significant proportion of observed antifungal activity of initial butanol fraction from A. lobatum. Further analysis of these sub-fractions and determination of structure would provide the shortlist for novel compounds that can be a lead to new agrochemicals.
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