Differential regulation of metalloproteinase production, proliferation and chemotaxis of human lung fibroblasts by PDGF, Interleukin-1β and TNF-α

Autor: Masahiro Sasaki, Masayuki Kashima, Takefumi Ito, Akiko Watanabe, Noriko Izumiyama, Masaaki Sano, Manabu Kagaya, Takanobu Shioya, Mamoru Miura
Jazyk: angličtina
Rok vydání: 2000
Předmět:
Zdroj: Mediators of Inflammation, Vol 9, Iss 3-4, Pp 155-160 (2000)
Druh dokumentu: article
ISSN: 0962-9351
1466-1861
45243603
DOI: 10.1080/09629350020002895
Popis: Fibroblast migration, proliferation, extracellular matrix protein synthesis and degradation,all of which play important roles in inflammation, are them selves induced by various growth factors and cytokines. Less is known about the interaction of these substances on lung fibroblast function in pulmonary fibrosis.
Databáze: Directory of Open Access Journals
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