A bivalent remipede toxin promotes calcium release via ryanodine receptor activation

Autor: Michael J. Maxwell, Chris Thekkedam, Cedric Lamboley, Yanni K.-Y. Chin, Theo Crawford, Jennifer J. Smith, Junyu Liu, Xinying Jia, Irina Vetter, Derek R. Laver, Bradley S. Launikonis, Angela Dulhunty, Eivind A. B. Undheim, Mehdi Mobli
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-023-36579-w
Popis: Insect toxins with tandem repeats of neurotoxin domains have been found with enhanced receptor avidity. Here, the authors describe a bivalent toxin from remipede venom that targets ryanodine receptors, a rare target for animal venoms.
Databáze: Directory of Open Access Journals