Clinical presentation of posterior cerebral artery occlusions – Clinical rationale for a more aggressive therapeutic strategy?

Autor: Volker Maus, Sophia Rogozinski, Jan Borggrefe, Utako Birgit Barnikol, Muharrem Saklak, Anastasios Mpotsaris
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: eNeurologicalSci, Vol 25, Iss , Pp 100368- (2021)
Druh dokumentu: article
ISSN: 2405-6502
DOI: 10.1016/j.ensci.2021.100368
Popis: Introduction: A proximal occlusion of the posterior cerebral artery (PCA) can affect patients severely and clinical outcome might be poor. Aim of this paper is to describe clinical presentation, diagnostic findings and outcome of patients suffering from ischemia in the PCA territory. Methods: We conducted a retrospective analysis of clinically affected patients with imaging-based evidence of ischemia within in the PCA territory at a comprehensive stroke center over a six-year period. Clinical (including demographics, National Institutes of Health Stroke Scale, NIHSS, modified Rankin Sclae, mRS), imaging (including occlusion site and brain infarction) and therapeutic data were evaluated. A favorable outcome was defined as an mRS ≤2. Results: Two hundred thirty-five patients were clinically affected with evidence of PCA ischemia detected by cross-sectional imaging. One-hundred fourty-five patients demonstrated an occlusion of the PCA including 43/145 (30%) with P1 occlusion, 80/145 (55%) with P2 and 22/145 (15%) with P3 occlusion. The most frequent symptom was hemi−/ quadrantanopsia (181/235, 77%). Sixty-eight patients (29%) suffered from hemiparesis. The occurrence of a hemiparesis was associated with a P1 occlusion (27/43, 63% vs. 41/192, 21%; p 2, 30/43, 70% vs. 55/192, 29%; p
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