Jungle yellow fever with positive serology for leptospira in a young peruvian male

Autor: Edinson Dante Meregildo-Rodriguez, Miguel Villegas-Chiroque
Jazyk: Spanish; Castilian
Rok vydání: 2019
Předmět:
Zdroj: Revista Peruana de Medicina Experimental y Salud Pública, Vol 36, Iss 4, Pp 700-4 (2019)
Druh dokumentu: article
ISSN: 1726-4634
1726-4642
DOI: 10.17843/rpmesp.2019.364.4347
Popis: Yellow fever (YF) and leptospirosis are under-diagnosed endemic zoonoses of the tropical regions of Africa and South America. Both may be clinically indistinguishable and present as an acute icterohemorrhagic febrile syndrome. We report the case of a 20-year-old male from the department of Amazonas who presented with nine days of disease characterized by multiorgan failure (neurological, renal, hepatic, respiratory, and hematological involvement). He received antibiotic treatment, as well as, transfusion, dialysis, hemodynamic, and ventilatory support. Despite the severity of the clinical condition, he evolved favorably. YF was confirmed by Rt-PCR and positive serology was obtained for leptospira by ELISA and microagglutination. However, from a laboratory point of view, real co-infection by yellow fever and leptospira could not be demonstrated. This case of severe YF with non-fatal outcome emphasizes the importance of adequate syndromic diagnosis, and early and aggressive supportive treatment that can save a patient's life.
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