Long-Term Response Rates to Infliximab Therapy for Crohn’s Disease in an Outpatient Cohort

Autor: Christopher W Teshima, Adrienne Thompson, LeRose Dhanoa, Levinus A Dieleman, Richard N Fedorak
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Canadian Journal of Gastroenterology, Vol 23, Iss 5, Pp 348-352 (2009)
Druh dokumentu: article
ISSN: 0835-7900
DOI: 10.1155/2009/180840
Popis: BACKGROUND: Infliximab’s efficacy in the induction and maintenance of remission in luminal Crohn’s disease has been confirmed by randomized, controlled trials. Less clearly described are long-term outcomes in the clinical practice setting since the establishment of regularly scheduled, every eight-week maintenance infliximab infusions. Existing reports describing clinical practice outcomes are limited by short durations of follow-up or by the use of episodic dosing, or focus on safety data rather than clinical outcomes.
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