| Autor: |
Romain Corroenne, Amy R. Mehollin-Ray, Rebecca M. Johnson, William E. Whitehead, Jimmy Espinoza, Jonathan Castillo, Heidi Castillo, Gunes Orman, Roopali Donepudi, Thierry A. G. M. Huisman, Ahmed A. Nassr, Michael A. Belfort, Magdalena Sanz Cortes, Alireza A. Shamshirsaz |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-021-92739-2 |
| Popis: |
Abstract To investigate the association of the myelomeningocele (MMC) volume with prenatal and postnatal motor function (MF) in cases who underwent a prenatal repair. Retrospective cohort study (11/2011 to 03/2019) of 63 patients who underwent a prenatal MMC repair (37 fetoscopic, 26 open-hysterotomy). At referral, measurements of the volume of MMC was performed based on ultrasound scans. A large MMC was defined as greater than the optimal volume threshold (ROC analysis) for the prediction of intact MF at referral (2.7 cc). Prenatal or postnatal intact motor function (S1) was defined as the observation of plantar flexion of the ankle based on ultrasound scan or postnatal examination. 23/63 participants presented a large MMC. Large MMC lesions was associated with an increased risk of having clubfeet by 9.5 times (CI%95[2.1–41.8], p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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