Cocirculation and replacement of SARS-CoV-2 variants in crowded settings and marginalized populations along the US-Mexico border

Autor: Antoine Chaillon, Ietza Bojorquez, Jaime Sepúlveda, Alicia Yolanda Harvey-Vera, M Gudelia Rangel, Britt Skaathun, Sanjay R Mehta, Caroline Ignacio, Magali Porrachia, Davey M Smith, Steffanie A Strathdee
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2023
Předmět:
Zdroj: Salud Pública de México, Vol 65, Iss 1, ene-feb, Pp 10-18 (2023)
Druh dokumentu: article
ISSN: 0036-3634
DOI: 10.21149/13980
Popis: Objective. To interrogate the circulating SARS-CoV-2 lin­eages and recombinant variants in persons living in migrant shelters and persons who inject drugs (PWID). Materials and methods. We combined data from two studies with marginalized populations (migrants in shelters and persons who inject drugs) in Tijuana, Mexico. SARS-CoV-2 variants were identified on nasal swabs specimens and compared to publicly available genomes sampled in Mexico and California. Results. All but 2 of the 10 lineages identified were predomi­nantly detected in North and Central America. Discrepan­cies between migrants and PWID can be explained by the temporal emergence and short time span of most of these lineages in the region. Conclusion. The results illustrate the temporo-spatial structure for SARS-CoV-2 lineage dispersal and the potential co-circulation of multiple lineages in high-risk populations with close social contacts. These conditions create the potential for recombination to take place in the California-Baja California border.
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