HEMOPHAGOCYTOSIS SECONDARY TO PHARYNGEAL ABSCESS IN AN IMMUNOCOMPETENT PATIENT (case report)
| Autor: | I. D. Khan, M. Malik, K. S. Rajmohan, P. Banerjee, S. Khan, P. S. Panda, M. Brijwal, S. Gupta, K. Kahkasha, S. Gazala, E. Sawarat, M. S. Aguinaga |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | International Journal of Medicine and Medical Research, Vol 0, Iss 1 (2018) |
| Druh dokumentu: | article |
| ISSN: | 2413-6077 2414-9985 |
| DOI: | 10.11603/ijmmr.2413-6077.2018.1.8514 |
| Popis: | Background. Hemophagocytosis is a rare, potentially fatal disorder, comprising pancytopenia, liver dysfunction, hepatosplenomegaly, hypertriglyceridemia, and hyperferritinemia presenting as fever, lymphadenopathy and skin rashes. Objective. To attract the clinicians’ attention to a problem of hemophagocytosis in Critical Care management. Methods. Hemophagocytosis secondary to pharyngeal abscess in a 58 year old male is being reported. Results. A 58-year-old immunocompetent patient presenting with hemophagocytosis secondary to pharyngeal abscess, was managed on ventilator and inotropic support, when he developed heathcare-associated urinary tract infection by Escherichia coli and ventilator-associated pneumonia by Acinetobacter baumanii. He developed neutropenic septic shock and multi-organ dysfunction and went through a downhill course leading to demise. Conclusions. Hemophagocytosis remains a sinister entity in modern intensive care despite astute clinical management. Secondary superinfections with opportunistic multidrug resistant pathogens are difficult to treat. A high index of clinical suspicion, aggressive diagnosis and prompt treatment for hemophagocytosis and polymicrobial opportunistic superinfections with multidrug-resistant healthcare-associated pathogens needs to be addressed upfront. |
| Databáze: | Directory of Open Access Journals |
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