Associations of body size with all-cause and cause-specific mortality in healthy older adults

Autor: Prudence R. Carr, Katherine L. Webb, Johannes T. Neumann, Le T. P. Thao, Lawrence J. Beilin, Michael E. Ernst, Bernadette Fitzgibbon, Danijela Gasevic, Mark R. Nelson, Anne B. Newman, Suzanne G. Orchard, Alice Owen, Christopher M. Reid, Nigel P. Stocks, Andrew M. Tonkin, Robyn L. Woods, John J. McNeil
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-023-29586-w
Popis: Abstract In the general population, body mass index (BMI) and waist circumference are recognized risk factors for several chronic diseases and all-cause mortality. However, whether these associations are the same for older adults is less clear. The association of baseline BMI and waist circumference with all-cause and cause-specific mortality was investigated in 18,209 Australian and US participants (mean age: 75.1 ± 4.5 years) from the ASPirin in Reducing Events in the Elderly (ASPREE) study, followed up for a median of 6.9 years (IQR: 5.7, 8.0). There were substantially different relationships observed in men and women. In men, the lowest risk of all-cause and cardiovascular mortality was observed with a BMI in the range 25.0–29.9 kg/m2 [HR25-29.9 vs 21–24.9 kg/m 2: 0.85; 95% CI, 0.73–1.00] while the highest risk was in those who were underweight [HRBMI
Databáze: Directory of Open Access Journals
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