Human Gyrovirus DNA in Human Blood, Italy

Autor:	Fabrizio Maggi, Lisa Macera, Daniele Focosi, Maria Linda Vatteroni, Ugo Boggi, Guido Antonelli, Marc Eloit, Mauro Pistello
Jazyk:	angličtina
Rok vydání:	2012
Předmět:	human gyrovirus HGyV DNA transplantation HIV real-time PCR sequencing Medicine Infectious and parasitic diseases RC109-216
Zdroj:	Emerging Infectious Diseases, Vol 18, Iss 6, Pp 956-959 (2012)
Druh dokumentu:	article
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid1806.120179
Popis:	Human gyrovirus (HGyV) is a recent addition to the list of agents found in humans. Prevalence, biologic properties, and clinical associations of this novel virus are still incompletely understood. We used qualitative PCRs to detect HGyV in blood samples of 301 persons from Italy. HGyV genome was detected in 3 of 100 solid organ transplant recipients and in 1 HIV-infected person. The virus was not detected in plasma samples from healthy persons. Furthermore, during observation, persons for whom longitudinal plasma samples were obtained had transient and scattered presence of circulating HGyV. Sequencing of a 138-bp fragment showed nucleotide identity among all the HGyV isolates. These results show that HGyV can be present in the blood of infected persons. Additional studies are needed to investigate possible clinical implications.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/cfe82271c8054088b37da67b251e9bc2 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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