Human Milk Oligosaccharides (HMOs) and Infant Microbiota: A Scoping Review

Autor: Cristina Sánchez, Cristina Fente, Patricia Regal, Alexandre Lamas, María Paz Lorenzo
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Foods, Vol 10, Iss 6, p 1429 (2021)
Druh dokumentu: article
ISSN: 2304-8158
DOI: 10.3390/foods10061429
Popis: Human milk oligosaccharides (HMOs) are the third most abundant solid component of breast milk. However, the newborn cannot assimilate them as nutrients. They are recognized prebiotic agents (the first in the newborn diet) that stimulate the growth of beneficial microorganisms, mainly the genus Bifidobacterium, dominant in the gut of breastfed infants. The structures of the oligosaccharides vary mainly according to maternal genetics, but also other maternal factors such as parity and mode of delivery, age, diet, and nutritional status or even geographic location and seasonality cause different breast milk oligosaccharides profiles. Differences in the profiles of HMO have been linked to breast milk microbiota and gut microbial colonization of babies. Here, we provide a review of the scope of reports on associations between HMOs and the infant gut microbiota to assess the impact of HMO composition.
Databáze: Directory of Open Access Journals