Diagnostic Performance of Diffusion-Weighted MRI and FDG PET/CT for Detecting the Local Recurrence of Head and Neck Squamous Cell Carcinoma

Autor: İbrahim İlker Öz, İsmail Şerifoğlu, Yavuz Sami Salihoğlu, Murat Damar, Aykut Erdem Dinç, Rabiye Uslu, Mustafa Çağatay Büyükuysal, Oktay Erdem
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: İstanbul Medical Journal, Vol 17, Iss 2, Pp 48-53 (2016)
Druh dokumentu: article
ISSN: 2619-9793
2148-094X
DOI: 10.5152/imj.2016.15010
Popis: Objective: To compare the efficacy between diffusion-weighted magnetic resonance imaging (DW-MRI) and positron emission tomography/computed tomography (PET/CT) in detecting the local recurrence of head and neck squamous cell carcinoma (HNSCC) following treatment in the same patient group.Methods: Twenty-three patients who had biopsy-proven HNSCC were enrolled. All patients were treated with radiotherapy and followed up with MRI and PET/CT. The median delay times between radiotherapy and MRI and between MRI and FDG PET/CT were 71 days (range: 43–98 days) and 75 days (range: 44–103 days), respectively. Diffusion-weighted single-shot echo planar imaging was performed before contrast injection at b values of 0 and 1000 s/ mm2. PET/CT images were acquired after the administration of 3.7 MBq/kg of fluorine-18-fluorodeoxyglucose, and the images were acquired 1 h later.Results: The apparent diffusion coefficient (ADC)mean values of the recurrence group were significantly lower than those of the post-treatment changes group (0.773 vs. 1.588×10−3 mm2/s, respectively; p
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