Gastrotomy followed by gastrorrhaphy as a reliable and more physiologic technique for inducing peritoneal adhesion in rats
| Autor: | ANTONIO AUGUSTO RIBEIRO DIAS PIRES, CHRISTINA MAEDA TAKIYA, PAULO CESAR SILVA, JOSÉ EDUARDO FERREIRA MANSO |
|---|---|
| Jazyk: | English<br />Spanish; Castilian<br />Portuguese |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Revista do Colégio Brasileiro de Cirurgiões, Vol 50 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1809-4546 0100-6991 |
| DOI: | 10.1590/0100-6991e-20233453-en |
| Popis: | ABSTRACT Objective: this research objective was to develop a new peritoneal adhesion animal model that would lead to adhesions formation in all operated animals, simple and reproducible, associated with maintenance the animal’s health. Methods: eighteen adult male Wistar rats (Rattus norvegicus) were randomly distributed into three groups: Control Group (anatomical and clinical parameters), Sham Group (delicate manipulation of the stomach and exposure of the peritoneal cavity to ambient air) and Surgery Group (gastrotomy followed by gastrorrhaphy). The animals were analyzed and classificated macroscopically according to two adhesion classification models and differences between groups were considered significant when p |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|