Lipid accumulation product (LAP) index as a potential risk assessment for cardiovascular risk stratification among type II diabetes mellitus in a Ghanaian population: A cross-sectional study

Autor: Evans Asamoah Adu, Christian Obirikorang, Emmanuel Acheampong, Aaron Siaw Kwakye, Foster Fokuoh, Yaa Obirikorang, Enoch Odame Anto, Emmanuella Nsenbah Batu, Brodrick Yeboah Amoah, Patience N. Ansong
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Cogent Medicine, Vol 6, Iss 1 (2019)
Druh dokumentu: article
ISSN: 2331-205X
2331205X
DOI: 10.1080/2331205X.2019.1639880
Popis: The study determined the comparative usefulness of Lipid Accumulation Product (LAP) index, for identifying individuals at immediate risk of cardiovascular diseases in a Ghanaian population. A cross-sectional study that involved 324 T2DM patients attending the Eastern Regional Hospital, Koforidua, Ghana was selected using a simple random sampling method. Height, body weight, and waist circumference (WC) of all study participants were measured; Body Mass Index (BMI) was derived from the measurements of height and weight. Fasting blood samples were collected for lipids and glucose measurements. Lipid accumulation product index was estimated from waist circumference and plasma triglycerides concentration. Ten-year risk of general CVD morbidity was estimated using the Framingham risk estimation criteria. Mean age of the study participants was 57.2 (±7.2 SD). LAP index (z-scores) was significantly associated and predictive of Metabolic Syndrome (MetS) by IDF [OR = 11.91 (4.76–29.75), p-value
Databáze: Directory of Open Access Journals
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