Long-term Impact of Cardiorespiratory Fitness on Type 2 Diabetes Incidence: A Cohort Study of Japanese Men

Autor: Ryoko Kawakami, Susumu S. Sawada, I-Min Lee, Yuko Gando, Haruki Momma, Shin Terada, Chihiro Kinugawa, Takashi Okamoto, Koji Tsukamoto, Mitsuru Higuchi, Motohiko Miyachi, Steven N. Blair
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Journal of Epidemiology, Vol 28, Iss 5, Pp 266-273 (2018)
Druh dokumentu: article
ISSN: 0917-5040
1349-9092
20170017
DOI: 10.2188/jea.JE20170017
Popis: Background: We sought to examine the association between cardiorespiratory fitness (CRF) and incidence of type 2 diabetes considering the follow-up period in a cohort of Japanese men with a maximum follow-up period of 23 years. Methods: This study enrolled 7,804 male workers free of diabetes in 1986. CRF was measured using a cycle ergometer, and maximal oxygen uptake was estimated. During 1986–2009, participants were followed for development of type 2 diabetes, which was diagnosed using fasting blood tests, self-administered questionnaires, or oral glucose tolerance tests after urinary tests from annual health checkups. Hazard ratios for the incidence of type 2 diabetes were estimated using Cox proportional hazards models. Results: During the follow-up period, 1,047 men developed type 2 diabetes. In analyses by follow-up periods (1986–1993, 1994–2001, and 2002–2009), there was an inverse dose-response relationship between CRF and the development of type 2 diabetes for all three follow-up periods (P for trend 0.019, 20 years among men.
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