| Autor: |
Gerold eBaier, Marc eGoodfellow, Peter Neal Taylor, Yujiang eWang, Daniel James Garry |
| Jazyk: |
angličtina |
| Rok vydání: |
2012 |
| Předmět: |
|
| Zdroj: |
Frontiers in Physiology, Vol 3 (2012) |
| Druh dokumentu: |
article |
| ISSN: |
1664-042X |
| DOI: |
10.3389/fphys.2012.00281 |
| Popis: |
The occurrence of seizures is the common feature across the spectrum of epileptic disorders. We describe how the use of mechanistic neural population models leads to novel insight into the dynamic mechanisms underlying two important types of epileptic seizures. We specifically stress the need for a spatio-temporal description of the rhythms to deal with the complexity of the pathophenotype. Adapted to functional and structural patient data, the macroscopic models may allow a patient-specific description of seizures and prediction of the impact of specific interventions. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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