Sex Differences in Physical Activity and Its Association With Cardiac Death and All-Cause Mortality in Patients With Implantable Cardioverter-Defibrillators

Autor: Xiaoyao Li, Xiaodi Xue, Xuerong Sun, Shuang Zhao, Keping Chen, Wei Hua, Yangang Su, Jiefu Yang, Zhaoguang Liang, Wei Xu, Zeyi Li, Shu Zhang
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Druh dokumentu: article
ISSN: 2297-055X
DOI: 10.3389/fcvm.2020.588622
Popis: Objective: To clarify the impact of sex on physical activity (PA) levels among patients with implantable cardioverter-defibrillators/cardiac resynchronization therapy defibrillators (ICD/CRT-D) and its association with cardiac death and all-cause mortality.Methods: Overall, data of 820 patients with ICD/CRT-D from the SUMMIT registry were retrospectively analyzed. Baseline PA from 30 to 60 days after device implantation was measured using Biotronik accelerometer sensors. The primary and secondary endpoints were cardiac death and all-cause mortality, respectively.Results: Baseline PA levels were significantly higher in male patients than in female patients (11.40 ± 5.83% vs. 9.93 ± 5.49%, P = 0.001). Males had higher predictive PA cut-off values for cardiac death (11.16 vs. 7.15%) and all-cause mortality (11.33 vs. 7.17%). During the median follow-up time of 75.7 ± 29.1 months, patients with baseline PA
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