| Autor: |
Dvora Joseph Davey, Dorothy C. Nyemba, Jose Castillo‐Mancilla, Lubbe Wiesner, Jennifer Norman, Rufaro Mvududu, Nyiko Mashele, Leigh F. Johnson, Linda‐Gail Bekker, Pamina Gorbach, Thomas J. Coates, Landon Myer |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Journal of the International AIDS Society, Vol 25, Iss 12, Pp n/a-n/a (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1758-2652 |
| DOI: |
10.1002/jia2.26044 |
| Popis: |
Abstract Introduction Daily oral pre‐exposure prophylaxis (PrEP) can reduce HIV acquisition. However, prevention effectiveness requires daily adherence prior to and during periods of sexual activity. Little is known about pharmacologic measures of PrEP adherence during pregnancy and postpartum and the factors related to optimal adherence during periods of sexual activity in this population. Methods Between August 2019 and October 2021, we enrolled pregnant women without HIV at their first antenatal care visit followed‐up through 12 months postpartum. Eligible women ≥16 years old received HIV prevention counselling and were offered oral PrEP (TDF‐FTC). We quantified tenofovir‐diphosphate (TFV‐DP) in dried blood spots in women who reported taking PrEP in the past 30 days (at quarterly follow‐up visits). We used regression models with generalized estimating equations to evaluate correlates of TFV‐DP (any vs. none, and ≥2 vs. 5/month vs. no sex or |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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