| Autor: |
Bao N. Nguyen, Rekha Srinivasan, Allison M. McKendrick |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
IBRO Neuroscience Reports, Vol 14, Iss , Pp 419-427 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2667-2421 |
| DOI: |
10.1016/j.ibneur.2023.04.003 |
| Popis: |
In healthy adults with normal vision, temporary deprivation of one eye’s visual experience produces transient yet robust homeostatic plasticity effects, where the deprived eye becomes more dominant. This shift in ocular dominance is short-lived and compensatory. Previous work shows that monocular deprivation decreases resting state gamma aminobutyric acid (GABA; inhibitory neurotransmitter) levels in visual cortex, and that those with the greatest reduction in GABA have stronger shifts due to monocular deprivation. Components of the GABAergic system in visual cortex vary with age (early childhood, early teen years, ageing); hence if GABA is critical to homeostatic plasticity within the visual system, adolescence may be a key developmental period where differences in plasticity manifest. Here we measured short-term visual deprivation effects on binocular rivalry in 24 adolescents (aged 10–15 years) and 23 young adults (aged 20–25 years). Despite differences in baseline features of binocular rivalry (adolescents showed more mixed percept p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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