Content aware image restoration improves spatiotemporal resolution in luminescence imaging

Autor: Tobias Boothe, Mario Ivanković, Markus A. Grohme, M. Andrea Markus, Christian Dullin, Xingbo Xu, Jochen C. Rink
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Communications Biology, Vol 6, Iss 1, Pp 1-7 (2023)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-023-04886-z
Popis: Abstract Luminescent reporters are due to their intrinsically high signal-to-noise ratio a powerful labelling tool for microscopy and macroscopic in vivo imaging in biomedical research. However, luminescence signal detection requires longer exposure times than fluorescence imaging and is consequently less suited for applications requiring high temporal resolution or throughput. Here we demonstrate that content aware image restoration can drastically reduce the exposure time requirements in luminescence imaging, thus overcoming one of the major limitations of the technique.
Databáze: Directory of Open Access Journals
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