| Autor: |
Shiming Cheng, Wei Chen, Yingzhou Yang, Ping Chu, Xiaoli Liu, Meigui Zhao, Weiguo Tan, Li Xu, Qingfang Wu, Hongyun Guan, Jinhong Liu, Haitao Liu, Ray Y Chen, Zhongwei Jia |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
PLoS ONE, Vol 8, Iss 6, p e67516 (2013) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0067516 |
| Popis: |
IntroductionTo understand better the risk of tuberculosis transmission with increasing delay in tuberculosis treatment, we undertook a retrospective cohort study in Shenzhen, China.MethodsAll pulmonary tuberculosis cases in the Shenzhen tuberculosis surveillance database from 1993-2010 were included. Sputum smear positivity and presence of pulmonary cavity were used as proxies for risk of tuberculosis transmission.ResultsAmong 48,441pulmonary tuberculosis cases, 70% presented with symptoms of pulmonary TB, 62% were sputum smear positive, and 21% had a pulmonary cavity on chest x-ray. 95.3% of patients self-presented for evaluation of illness after a median 58 days of delay after symptoms began. The proportion presenting sputum smear positive (pConclusionsDelayed diagnosis and treatment of tuberculosis is associated with a significantly increased risk of pulmonary sputum smear positivity and pulmonary cavity. To decrease risk of transmission, treatment delay needs to be reduced further. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
