| Popis: |
Takanori Ikeda,1 Masahiro Yasaka,2 Makoto Kida,3 Miki Imura4 1Department of Cardiovascular Medicine, Toho University Faculty of Medicine, Tokyo, 2Department of Cerebrovascular Medicine and Neurology, National Hospital Organization, Kyushu Medical Center, Fukuoka, 3Medical & Development, Bristol-Myers Squibb KK, Tokyo, 4PIH Medical Affairs, Pfizer Japan Inc, Tokyo, Japan Purpose: Although warfarin has historically been the standard of care for preventing ischemic stroke in patients with nonvalvular atrial fibrillation (NVAF), the use of direct oral anticoagulants (DOACs) is rapidly increasing. In this study, we examined the demographic and clinical characteristics of patients continuing warfarin therapy and investigated reasons for warfarin continuation.Patients and methods: Each study site consecutively registered 10 patients with NVAF who had been taking warfarin for at least 12 months. Demographic and clinical characteristics and international normalized ratio (INR) values were collected from medical records. Physicians responded to questionnaires exploring reasons for continuing warfarin therapy.Results: Overall, 313 patients treated with warfarin were registered at 33 sites. Mean ± SD age was 76.4±9.6 years; 62.9% of patients were male. The proportion of patients with INR values in the therapeutic range was 74.6% and 48.8% among patients aged ≥70 years and |
