Are Lactoferrin and Interleukine-6 preterm birth participants?
| Autor: | Veronica Cotelea, Natalia Corolcova, Luminita Mihalcean, Mihaela Burac, Liliana Profire, Iurie Dondiuc |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | The Moldovan Medical Journal, Vol 66, Iss 2, Pp 20-23 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2537-6373 2537-6381 |
| DOI: | 10.52418/moldovan-med-j.66-2.23.03 |
| Popis: | Background: Preterm birth remains a leading obstetrical complication because of the incomplete understanding of its multifaceted etiology. It is known that immune alterations toward a proinflammatory profile are observed in women with preterm birth, but therapeutic interventions are still lacking because of scarcity of evidence in the integration of maternal and placental interrelated compartments. Objective: To investigate value of Lactoferrin (LF) and Interleukine-6 (IL-6) in the preterm labor. Material and methods: The study comprised 65 women with spontaneous preterm labor and 65 women with term labor. Maternal plasma concentrations of Lactoferrin and Interleukine-6 were detected by standard test system Aeskulisa Lactoferrin and Best-Vector A-8768 for Interleukine-6 Ref 3307 which (GmbH & Co, Germany) gave an analytical sensitive of 1.0 U/ml for Lactoferrin and 0.131 pg/ml for Interleukine-6. Results: Plasma levels of Lactoferrin in women with preterm labor were lower (µmedian = 0.90 U/ml) (p |
| Databáze: | Directory of Open Access Journals |
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