HOTAIR regulates SIRT3-mediated cardiomyocyte survival after myocardial ischemia/reperfusion by interacting with FUS

Autor:	Jixuan Liu, Mingzhuang Sun, Jinda Wang, Zhijun Sun, Gang Wang
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	lncRNA HOTAIR SIRT3 FUS Myocardial ischemia/reperfusion Cardiomyocyte survival Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-12 (2023)
Druh dokumentu:	article
ISSN:	1471-2261
DOI:	10.1186/s12872-023-03203-0
Popis:	Highlights 1. Overexpression of HOTAIR or SIRT3 promotes H/R-induced cardiomyocyte survival. 2. LncRNA HOTAIR regulates the expression of SIRT3 by binding to FUS. 3. HOTAIR/FUS/SIRT3 axis facilitates cardiomyocyte survival under H/R treatment.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/fdc1ea1972e74db3b644ee687c751f96 Zobrazit plný text záznamu Full text from SpringerLink View record in DOAJ