HIV Status and Other Risk Factors for Prevalent and Incident Sexually Transmitted Infection during Pregnancy (2000-2014)

Autor: Jodie Dionne-Odom, Michelle J. Khan, Victoria C. Jauk, Jeff Szychowski, Dustin M. Long, Suzanne Wallace, Cherry Neely, Karen Fry, Jeanne Marrazzo, Marilyn Crain, Alan T. N. Tita
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Infectious Diseases in Obstetrics and Gynecology, Vol 2019 (2019)
Druh dokumentu: article
ISSN: 1064-7449
1098-0997
DOI: 10.1155/2019/6584101
Popis: Background. Sexually transmitted infections (STIs) are associated with adverse birth outcomes. Current prenatal STI screening guidelines define “risk” without explicit consideration of HIV status. Our objective was to test the hypothesis that HIV status is associated with bacterial STI in pregnant women. Methods. We designed a retrospective cohort study to identify pregnant women with HIV who delivered at our facility during 2000-2014. HIV+ women were compared to HIV- women with matching by year of delivery. Logistic regression was used to model adjusted odds of prevalent and incident STI. Prevalent STI was defined as chlamydia (CT), gonorrhea (GC), syphilis, or trichomoniasis detected on an initial prenatal screening test and incident STI as a newly positive result following a negative prenatal test. Results. The cohort included 432 women, 210 HIV+ and 222 HIV-. Most pregnant women were screened for STI (92% of HIV+ women and 74% of HIV- women). STI rates were high and particularly elevated in HIV+ women: 29% vs 18% (p=0.02), for prevalent STI and 11% vs 2% (p
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