The Potential Benefits and Adverse Effects of Phytic Acid Supplement in Streptozotocin-Induced Diabetic Rats
| Autor: | F. O. Omoruyi, A. Budiaman, Y. Eng, F. E. Olumese, J. L. Hoesel, A. Ejilemele, A. O. Okorodudu |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Advances in Pharmacological Sciences, Vol 2013 (2013) |
| Druh dokumentu: | article |
| ISSN: | 1687-6334 1687-6342 |
| DOI: | 10.1155/2013/172494 |
| Popis: | In this study, the effect of phytic acid supplement on streptozotocin-induced diabetic rats was investigated. Diabetic rats were fed rodent chow with or without phytic acid supplementation for thirty days. Blood and organ samples were collected for assays. The average food intake was the highest and the body weight gain was the lowest in the group fed phytic acid supplement compared to the diabetic and normal control groups. There was a downward trend in intestinal amylase activity in the group fed phytic acid supplement compared to the other groups. The spike in random blood glucose was the lowest in the same group. We noted reduced serum triglycerides and increased total cholesterol and HDL cholesterol levels in the group fed phytic acid supplement. Serum alkaline phosphatase and alanine amino transferase activities were significantly (P |
| Databáze: | Directory of Open Access Journals |
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